NVIDIA Nemotron agents on Nebius, powered by NVIDIA Parabricks, take raw DNA to an answer. Watch the whole Run as it happens; approve at the key points.
Real result on HG001, a public reference sample, from the demo Run (#457, an earlier build) and Run H R21 R3. Research use, not medical advice.
More and more studies, in many fields, need genetic evidence. The reads are cheap now. The bioinformatics is not: it is still slow, specialised work, and many researchers have no team for it.
A coding agent might come back with the variant. But which reference did it use? Which allele did it mean? Did it read a missing record as "not carried"? And if one step was wrong, how do you fix only that step?
Traceome isn't a smarter agent. Every step goes on a record the agent cannot rewrite and the researcher can always read. When the evidence conflicts, the agent asks the researcher, and only that item waits.
The researcher brings a question, a paper or a list of variants, and the raw reads. A planning agent identifies the reference genome and prepares everything the alignment needs.
Does HG001 carry rs4149056?
+ 28 more targets · BRAF V600E · FASTQ pair
ReferenceGRCh38
Once the researcher approves the plan, Parabricks aligns the reads and calls the variants as a Nebius Serverless AI job on an H100. The output files are verified before anything builds on them.
BAMverified
VCF · 260,016 recordsverified
An agent looks up each variant in NCBI and EVA. One rsID can hide two different letter changes, or have been merged into another. Each becomes an exact Work item for the researcher to approve.
T → Awork item
T → Cwork item
rs9999999999unresolved
Each answer comes from the sample's own data. "No record" is never turned into "not carried". When the evidence conflicts, the agent asks the researcher, and only that item waits.
T → Cobserved · 0/1 · depth 26
T → Anot carried
An agent writes the findings up in plain words. It may cite only approved facts, and every citation opens that fact in the Journey.
"…the exact T>C allele at 21178615 is carried (heterozygous 0/1), while the T>A target at that same position is not carried. [3b84b6f1…]"
Each number is from one development Run and opens its evidence. A small evaluation shows the first patterns; a bigger one is planned.
The player appears here once the video is published.
The demo Run on a human genome, replayed in the real GUI: stages, answers, evidence, approvals.
02Stage by stageWhat each of the five stages does, who does it, and what is kept.
03Proof and limitsEvery claim with its Run, and what Traceome is not.
04TechnologyArchitecture, agent tools, the Journey and the measurements.